HMGCR antibodies. HMGCR Antibody, Biotin conjugated ( ELISA ) ( CSB-PA010565LD01HU ) HMGCR Antibody, HRP conjugated ( ELISA ) ( CSB-PA010565LB01HU ) HMGCR Antibody, FITC conjugated ( ELISA ) ( CSB-PA010565LC01HU ) HMGCR Antibody ( ELISA,IHC ) ( CSB-PA031676 ) HMGCR Antibody ( ELISA,IHC ) ( CSB-PA929004 ) More>> HMGCR Proteins

FAQs for HMG-CoA Reductase/HMGCR Antibody (NBP1-91996). (Showing 1 - 1 of 1 FAQs). If we use this antibody for western blot, what is the predicted protein size? HMGCR is a 887 amino acids long protein with a predicted size of 96.7 kDa.

VvG stain: Myopathic features Muscle fibers Internal architecture: May have aggregates Size: Varied HMGCR is a key enzyme in cholesterol biosynthesis. Anti‐HMGCR antibodies are considered relatively specific for necrotizing myositis and are usually associated with statin exposure 12, 13. As a single case report, the presented clinical and laboratory findings can only be considered hypothesis generating. Statins and myositis: the role of anti-HMGCR antibodies Muscle toxicity is a recognized adverse effect of statin use. Recently, a new myositis syndrome was described in association with antibodies directed against the pharmacologic target of statins, anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR antibody).

Hmgcr antibody

It is reactive with 3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.34; UniProt P00347; also known as HMG-CoA reductase) is encoded by the HMGCR gene (Gene ID anti-HMGCR Antibody reacting with Rabbit and identified with ELISA, WB, IHC, IF . Quality is guaranteed. Immunofluorescence analysis of A549 cell using HMGCR antibody. Blue: DAPI for nuclear staining. Rabbit anti-HMGCR Antibody. Rabbit polyclonal anti-HMGCR antibody (STJ24046) is suitable for use in Western Blot and Immunohistochemistry.

HMGCR is a key enzyme in cholesterol biosynthesis. Anti‐HMGCR antibodies are considered relatively specific for necrotizing myositis and are usually associated with statin exposure 12, 13. As a single case report, the presented clinical and laboratory findings can only be considered hypothesis generating. It is unclear whether anti‐HMGCR

HMGCR Antibody (PA5-37367) in WB Western blot analysis of HMGCR in extracts of various cells using HMGCR polyclonal antibody (Product # PA5-37367). HMGCR antibody Rabbit Polyclonal from Proteintech validated in Immunohistochemistry (IHC), Immunofluorescence (IF),Enzyme-linked Immunosorbent Assay (ELISA) applications. This antibody reacts with human, mouse, rat samples.

1. Anti-HMGCR antibody detection. Anti-HMGCR antibodies were measured by two ELISA tests (one home-made, one commercial) and confirmed by

This antibody reacts with human, mouse, rat samples.

Many cases are associated with statin exposure although this is not universal. In those with statin exposure the myositis does not resolve with drug cessation. HMGCR Antibody: Chronic Myopathy, Young onset. VvG stain: Myopathic features Muscle fibers Internal architecture: May have aggregates Size: Varied Regenerating muscle fibers: Scattered Endomysial connective tissue: Increased Severity of pathology: May vary among fascicles. HMGCR : Necrotizing autoimmune myopathy (NAM) is a serious but rare muscle disease strongly associated with autoantibodies to either signal recognition protein (SRP) or 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR).(1) NAM typically manifests with subacute proximal limb muscle weakness and persistently elevated serum creatine kinase (CK) concentrations, but slower onsets can occur and HMGCR is a key enzyme in cholesterol biosynthesis.
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We assessed anti-HMGCR antibodies in patients with suspected IMNM following statin exposure and patients with other autoimmune rheuma … Mouse monoclonal HMGCR antibody [CL0260]. Validated in WB, IHC and tested in Human. Cited in 2 publication(s).

HMGCR Ab Necrotizing autoimmune myopathy (NAM) HMGCR Antibodies Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal Necrotizing autoimmune myopathy (NAM) is a serious but rare muscle disease strongly associated with autoantibodies to either signal recognition protein (SRP) or 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR). HMGCR Abs (3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase) are associated with necrotizing myopathy that is commonly related to statin exposure. Recently, auto-antibodies (AAbs) to the enzyme, 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) was shown to be a MSA that was strongly associated with immune mediated necrotising myopathy (Arthritis Rheum.
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antikroppar (MSA) Courtesy H. Gunawardena Anti- HMGCR Gunawardena H. Myositis Autoantibody Subsets MAA = myositis associated antibody Pro babili

HMGCR Abs (3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase) are associated with necrotizing myopathy that is commonly related to statin exposure. Recently, auto-antibodies (AAbs) to the enzyme, 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) was shown to be a MSA that was strongly associated with immune mediated necrotising myopathy (Arthritis Rheum.

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Product Name: HMGCR antibody: Catalog Number: orb228653: Species/Host: Rabbit: Reactivity: Human, Mouse, Rat: Conjugation: Unconjugated: Tested applications: IHC-P, WB

Cited in 53 publication(s). Independently reviewed in 5 review(s). HPA008338 Sigma-Aldrich Anti-HMGCR antibody produced in rabbit Prestige Antibodies ® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution . Synonym: Anti-3-Hydroxy-3-methylglutaryl-CoA reductase Human Protein Atlas Number HPA008338 Human Protein Atlas - View RNA & protein expression data of this target View application images and datasheets for 163 anti HMGCR Antibody antibodies from 20 leading antibody suppliers, plus reviews and the top related antibodies Immunohistochemistry of paraffin-embedded human small intestine using HMGCR antibody (STJ24046) at dilution of 1:200 (40x lens). Western blot analysis of extracts of Rat brain, using HMGCR Rabbit pAb (STJ24046) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL HMGCR antibody LS-C318764 is an HRP-conjugated rabbit polyclonal antibody to human HMGCR (HMG-CoA Reductase). Validated for ELISA, IHC and WB. HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase) is a Protein Coding gene. Diseases associated with HMGCR include Familial Hyperlipidemia and Sitosterolemia.Among its related pathways are Sterol Regulatory Element-Binding Proteins (SREBP) signalling and … HMGCR antibodies; LDLCQ3 antibodies; Custom Antibodies.